How DMSO Works in the Body
DMSO is one of those substances that people hear about, but don’t fully understand. It’s important to know how DMSO works in your body.
Some say it helps with pain. Others talk about how quickly it absorbs into the body. And then there are those who warn against it altogether.
So what’s really going on?
In simple terms, DMSO (dimethyl sulfoxide) is known for its ability to move through the skin and carry certain compounds with it. That unique property is what makes it so interesting—and also why it raises questions.
In this article, we’ll take a straightforward look at how DMSO works in the body, what makes it different, and why it has gained so much attention in natural health circles.
What You’ll Learn in This Article
- What DMSO is and where it comes from
- How it moves through the skin and into the body
- Why people use it for pain and inflammation
- What makes it different from other topical substances
- Important considerations before using it
What Is DMSO?
DMSO (dimethyl sulfoxide) is a sulfur-based compound originally derived from wood pulp.
It has been studied for decades because of its unusual ability to pass through biological membranes, including the skin.
Unlike most topical products that stay on the surface, DMSO can move into the bloodstream relatively quickly. This is one of the key reasons it has attracted both interest and caution.
How DMSO Works and Moves Through the Body
One of the most unique features of DMSO is its ability to penetrate the skin.
When applied topically, it can:
- Pass through the outer layer of skin
- Enter the bloodstream
- Reach deeper tissues
This process happens more quickly than with many other substances.
Because of this, DMSO has been described as a “carrier,” meaning it may transport certain small molecules along with it as it moves through the body.
This is also why cleanliness is important when using it—anything on the skin at the time of application may also be carried inward.
Why DMSO Is Associated with Pain Relief
Many people are interested in DMSO because of its reported effects on discomfort.
While research is ongoing, DMSO has been studied for its potential to:
- Reduce inflammation
- Improve circulation in certain tissues
- Help relax muscles
Some users report that it works quickly compared to other topical approaches.
That said, individual experiences can vary, and responses may differ depending on how it is used.
What Makes DMSO Different?
DMSO stands out because of three key properties:
1. Rapid absorption
It moves through the skin quickly, rather than sitting on the surface.
2. Ability to carry substances
It may transport small molecules along with it into the body.
3. Deep tissue reach
It can affect areas beneath the skin rather than just the surface.
These qualities are what make DMSO unique—but also why it should be used thoughtfully.
Important Considerations About How DMSO Works
Because DMSO can carry substances into the body, skin cleanliness is especially important before application.
DMSO doesn’t just absorb on its own — it can also pull in residues left on the skin. This may include traces of:
- Soaps
- Lotions
- Perfumes
- Household or environmental chemicals
For that reason, it’s important to:
- Wash the area thoroughly beforehand
- Rinse well to remove any remaining residue
- Avoid applying over skin that may have been recently exposed to chemicals
In addition, be mindful of:
- The type and purity of the product
- Avoiding contact with unwanted substances during use
This unique property is part of what makes DMSO so widely discussed — and why it’s approached with both interest and caution.
Final Thoughts
DMSO is not a typical topical product.
Its ability to move through the skin and interact with deeper tissues is what makes it both fascinating and widely discussed.
Understanding how it works in the body is the first step in making informed decisions about its use.
As with any substance, it’s important to approach it with awareness and care. Please feel free to contact me with questions or comments.
Frequently Asked Questions About DMSO
What does DMSO do in the body?
DMSO is known for its ability to pass through the skin and move into the bloodstream and tissues. Because of this, it has been studied for its potential to support circulation, reduce inflammation, and interact with deeper layers of tissue rather than remaining on the surface like most topical products.
How quickly does DMSO absorb through the skin?
DMSO is absorbed relatively quickly compared to many topical substances. Some sources suggest it can begin moving through the skin within minutes, which is one reason it has attracted attention for its potential effects.
Why is it important to apply DMSO to clean skin?
DMSO can carry certain small molecules with it as it moves through the skin. This means that residues such as soaps, lotions, or other chemicals left on the skin could also be absorbed. For this reason, it’s important to wash and thoroughly rinse the area before applying.
Is DMSO the same as other topical pain relief products?
No. Most topical products remain on the surface of the skin and provide localized effects. DMSO is different because it can move through the skin and reach deeper tissues, which is part of what makes it unique. Minerals like magnesium also play a role in muscle relaxation.
Why is DMSO considered controversial?
DMSO has been widely studied and discussed for decades, but opinions about its use vary. Its ability to carry substances into the body raises both interest and caution, and this has contributed to ongoing debate around its use in different settings.
Can DMSO be used with other substances?
Because DMSO may carry certain compounds through the skin, combining it with other substances is something that should be approached carefully. This is one reason why awareness and caution are often emphasized in discussions about its use.
What makes DMSO different from other natural remedies?
DMSO stands out because of its ability to penetrate the skin and interact with deeper tissues. Most natural remedies work on the surface or through digestion, while DMSO’s unique absorption is what sets it apart.
About the Author
Pamela M. Rumley, ND is a Doctor of Naturopathy and natural health educator who writes about circulation, nutrition, oxygen delivery, and practical wellness strategies. She previously operated a natural health clinic where she worked directly with clients and studied techniques such as darkfield microscopy to observe live blood samples. Today she focuses on research, writing, and education to help readers better understand how the body works and how lifestyle choices can support long-term wellness.
Credentials
- Doctor of Naturopathy – Trinity School of Natural Health
• Master Herbalist – Dr. Christopher School of Natural Healing
• Certified Natural Health Professional – National Association of Certified Natural Health Professionals
• Former Natural Health Clinic Practitioner
• Training in Darkfield Microscopy and Live Blood Analysis
Learn more at PamRumley.com
